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Nezu (根津) was a parliament member who is also the leader of the terrorist resistance movement against the government.
Mr. Nezu provides information to the rest of the resistance as an undercover mole. He provides the IDs required to gain access to the military hospital. Ryu tells him of Kaneda's involvement with their plans. Nezu describes Neo-Tokyo as a rotting, over-ripe fruit with a new seed of hope inside it.
He can be seen at the meeting of the Supreme Executive Council smirking at the Colonel's frustration.
Nezu later appears in his estate during the Colonel's coup d'état, with his aides burning several documents, presumably containing corrupt and scandalous information. The aides kill themselves as a tank breaks through the main gate, and Nezu stuffs as much money as he can into a suitcase. Ryu appears, bloodied and mortally wounded, and tells him that the hospital plan was a failure. Nezu, convinced that Ryu 'sold him out,' shoots him on the spot.
Mr. Nezu attempts to escape the military through an alleyway, dragging his suitcase along with him. He's horrified to see Ryu still following him, half-dead. The shock from these causes him to have a heart attack. He desperately attempts to take his medication, stuffing dozens of pills into his mouth, but is unable to swallow them and keels over, dead.
He seems to be the mentor of Kei and Ryu and a follower of Lady Miyako and purports to be saving the nation from the corrupt and ineffective bureaucrats in power. It soon becomes evident, however, that Nezu is just as corrupt, and that all he seeks to do is to seize power for himself.
He later betrays Lady Miyako, as well as various other characters, as he attempts to take control of Akira. After losing Akira, he finds Ryu in a dark corridor with the boy in tow. He attempts to kill Ryu, thinking he is a member of Lady Miyako's group all along. Ryu, however, shoots Nezu. He fakes his death and later comes back.
It was Takashi's death at his hands that ignited the destruction of Neo-Tokyo by Akira.